The rash may look like other more common skin problems. Small, open sores may be present on mucous membranes. The sores may contain pus, or moist sores that look like warts may be present condyloma lata.
In dark-skinned people the sores may be a lighter color than the surrounding skin. A sore throat. A vague feeling of weakness or discomfort throughout the body. Weight loss.
Patchy hair loss, especially in the eyebrows, eyelashes, and scalp hair. Swelling of the lymph nodes. Nervous system symptoms of secondary syphilis, which can include neck stiffness, headaches, irritability, paralysis, unequal reflexes, and irregular pupils.
Latent hidden stage If untreated, an infected person will progress to the latent hidden stage of syphilis. Relapses of secondary syphilis About 20 to 30 out of people with syphilis have a relapse of the secondary stage of syphilis during the latent stage. Tertiary late stage This is the most destructive stage of syphilis. Complications of this stage include: Gummata, which are large sores inside the body or on the skin.
Cardiovascular syphilis, which affects the heart and blood vessels. Neurosyphilis, which affects the nervous system. References Citations Hook EW In L Goldman, A Shafer, eds. Antibiotics can cure syphilis and prevent more serious problems caused by it. You and your sex partner or partners need antibiotic treatment. This is to prevent passing the infection back and forth or to others.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor or nurse call line if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take. It's easier to prevent an STI than it is to treat one:. Ask your doctor for more information. Watch closely for changes in your health, and be sure to contact your doctor or nurse call line if:.
Enter Z in the search box to learn more about "Syphilis: Care Instructions". Author: Healthwise Staff. Kiley MD - Obstetrics and Gynecology. Care instructions adapted under license by your healthcare professional.
If you have questions about a medical condition or this instruction, always ask your healthcare professional. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. If the clinic contacts your previous sexual partners for you, your details will remain totally confidential and no information about you will be given out without your consent.
The treatment you need depends on how long you've had syphilis and how far along in your pregnancy you are.
Pregnant women who've had syphilis for less than 2 years are usually treated with an injection of penicillin into the buttocks if treated during the first or second trimester or 2 injections given a week apart if treated during the third trimester. Pregnant women who've had syphilis for more than 2 years are usually treated with 3 penicillin injections into the buttocks given at weekly intervals.
Page last reviewed: 07 February Next review due: 07 February Antibiotics for syphilis A short course of antibiotics can usually cure syphilis. The type of treatment you need depends on how long you've had syphilis. Follow-up blood tests will be recommended once treatment finishes to check that it has worked.
The rash usually does not cause itching. The characteristic rash of secondary syphilis may appear as rough, red, or reddish brown spots both on the palms of the hands and the bottoms of the feet.
However, rashes with a different appearance may occur on other parts of the body, sometimes resembling rashes caused by other diseases. Sometimes rashes associated with secondary syphilis are so faint that they are not noticed. Large, raised, gray or white lesions, known as condyloma lata, may develop in warm, moist areas such as the mouth, underarm or groin region.
In addition to rashes, symptoms of secondary syphilis may include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and fatigue. The symptoms of secondary syphilis will go away with or without treatment. However, without treatment, the infection will progress to the latent and possibly tertiary stage of disease.
The latent hidden stage of syphilis is a period of time when there are no visible signs or symptoms of syphilis. Without treatment, the infected person will continue to have syphilis in their body even though there are no signs or symptoms. Early latent syphilis is latent syphilis where infection occurred within the past 12 months.
Late latent syphilis is latent syphilis where infection occurred more than 12 months ago. Latent syphilis can last for years. Tertiary syphilis is rare and develops in a subset of untreated syphilis infections;, it can appear 10—30 years after infection was first acquired, and it can be fatal. Tertiary syphilis can affect multiple organ systems, including the brain, nerves, eyes, heart, blood vessels, liver, bones, and joints.
Symptoms of tertiary syphilis vary depending on the organ system affected. Syphilis can invade the nervous system neurosyphilis , visual system ocular syphilis , or auditory system otosyphilis at any stage of infection. These infections can cause a wide range of symptoms. When a pregnant woman has syphilis, the infection can be transmitted to her unborn baby. All pregnant women should be tested for syphilis at the first prenatal visit.
Some women need to be tested again during the third trimester 28 weeks gestation and at delivery. This includes women who live in areas of high syphilis morbidity, are previously untested, had a positive screening test in the first trimester, or are at higher risk for syphilis i. Depending on how long a pregnant woman has been infected, she may have a high risk of having a stillbirth or of giving birth to a baby who dies shortly after birth. Untreated syphilis in pregnant women results in infant death in up to 40 percent of cases.
An infected baby born alive may not have any signs or symptoms of disease. However, if not treated immediately, the baby may develop serious problems within a few weeks. Untreated babies may become developmentally delayed, have seizures, or die. All babies born to mothers who test positive for syphilis during pregnancy should be screened for syphilis and examined thoroughly for evidence of congenital syphilis.
Treponemal tests e.
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